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A legal analysis published in *Science* concluded that products marketed to slow aging and extend lifespan often meet the definition of drugs under U.S. law and may be subject to Food and Drug Administration regulation, even though aging is not classified as a disease. These products include metformin, rapamycin, compounds that promote NAD+ production, and resveratrol. None has been approved by the agency to combat aging, and approval for other medical uses does not establish its effectiveness for that purpose. Whether these products extend lifespan or increase the number of years people live in good health remains scientifically unresolved: answering that question requires long-term studies, and there is no consensus on reliable surrogate measures. The researchers therefore called for stronger evidence and greater oversight of the products and their ingredients.
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