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Scientists have uncovered more than a thousand precise proteins in the human brain that were absent from known protein maps, potentially opening new horizons for understanding brain aging and Alzheimer's disease. The team identified 1,067 proteins shorter than 150 amino acids using mass spectrometry techniques and machine learning. They found that levels of a particular protein known as "MKKS" were low in individuals with Alzheimer's and dementia. Although the study does not prove that this protein causes the disease, disabling it in brain cells weakened their ability to produce energy, suggesting its important role in brain biology and its possible link to the development of age-related diseases.
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