Scientists explain pregnant women's brain changes

A recent study has shown that elevated levels of estrogen during pregnancy cause a temporary impairment in memory, without affecting mood or overall activity. The increase in this hormone disrupts the function of the lateral hypothalamic area in the brain, reducing the activity of the neurotransmitter GABA and affecting communication with the CA3 region of the hippocampus, which is responsible for memory. Experiments also demonstrated that decreasing estrogen receptor levels in neurons can reverse the memory deficits associated with pregnancy. These cognitive changes are temporary and task-specific, not indicative of overall cognitive decline. It is believed that understanding this neural circuitry could later aid in developing treatments that target these pathways without compromising the beneficial effects of estrogen on the body.

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