Unknown illness causes kidney failure in healthy Texas workers

A mysterious form of kidney disease, known as chronic kidney disease of unknown etiology (CKDu) or Mesoamerican nephropathy, has been identified in Texas, mirroring cases previously reported among agricultural workers in Central America. The disease affects otherwise healthy young to middle-aged adults, particularly men in outdoor labor jobs, without typical risk factors such as diabetes or hypertension. Experts believe heat stress, dehydration, environmental toxins, and unsafe water may contribute to kidney damage, but the exact cause remains unknown, and there is no specific treatment. Many affected individuals are diagnosed only through routine screenings, often when the disease has progressed to an advanced stage.

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